Bishop Blake is the pastor of the West Angeles Church of God in Christ (COGIC), one of the largest churches in the Western United States, with a membership of over 24,000, starting with only 50 members in 1969 when he became pastor.
In 1982, he was selected by Ebony magazine as one of the 15 “Greatest Preachers in America”. Since 2007, Ebony has recognized Bishop Blake annually, as one of the 100+ most influential African Americans. Blake penned articles for Ebony and Christianity Today noting the importance of the Black churches influence on presidential elections. 
He has been a member of the General Board of COGIC since 1988.
Bishop Blake is an ardent advocate of education and academic excellence, who holds multiple academic and honorary degrees, from various educational institutions. Most recently, Biola University, conferred an honorary doctorate upon him on June 12, 2010.
In 2009 he was appointed as a member of Barack Obama‘s Inaugural Advisory Council of the Office of Faith-based and Neighborhood Partnerships where he served for one year on the council. In 2016, Bishop Blake was appointed as the Co-Chairperson to the leadership council of the Pentecostal/Charismatic Churches of North America. On November 15, 2016, Bishop Blake was reelected as the Presiding Bishop of the Church of God in Christ during the 2016 COGIC Election held by the COGIC General Assembly to a third four-year term.